Objective: Post-transcriptional modifications like m6A (N6-methyladenosine) and secondary structures like G-quadruplex (G4) are formations that play a vital role in RNA processing.Their synergy also has functional consequences.Since m6A is known to be enzymatically created in the DRACH-motif, and that genetic variants can create a novel DRACH-motif
Membrane heparan sulfate proteoglycans (HSPG) regulate cell proliferation, migration, and differentiation and are therefore considered key players in Refill cancer cell development processes.Here, we used the NT4 peptide to investigate how the sulfation pattern of HSPG on cells drives binding specificity.NT4 is a branched peptide that binds the gly
This study develops a method to use deep learning models to predict the mineral assemblages and their relative abundances in paleolake cores using high-resolution XRF core scan elemental data and X-ray diffraction (XRD) mineralogical results from the same core taken at coarser resolution.It uses the XRF core scan data along with published mineralog
The article presents the system for the automation of the design of the Slotted Spoon anchorage, which regulates the calculation of the required parameters of the fasteners for the fastening of the fastening system.The main factors affecting the operation of the anchor support are grouped in the following way: mining and geological conditions, tech